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Switching Antidepressants: What to Expect

Antidepressants are effective for treating depression in many people, and some are useful for combating anxiety. But no single antidepressant works best for everyone, and about one-half to two-thirds...

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Treatment-Resistant Depression

Depression affects about 16 million adults in the United States, and many people don’t respond to multiple attempts at treatment. Experts don’t fully understand why some individuals respond well while...

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Ketamine Clinics: What to Know

Evidence from multiple studies suggests that an intravenous (IV) infusion of ketamine, a drug that for decades has been used for anesthesia, may rapidly relieve symptoms of major depression,...

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A Nasal Spray for Major Depression?

In March 2019, the FDA announced the approval of the first wholly new medication to ease severe depression since fluoxetine (Prozac) debuted in 1988. The new treatment, a fast-acting nasal spray...

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Grin and Bear It? It Might Work

Grin and bear it: That adage may have practical value, according to an analysis of 138 studies about how facial expressions can influence emotional states, published in Psychological Bulletin. It found...

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Exercise vs. Depression

Exercise is an important—and often overlooked—strategy for both preventing and treating depression, according to a research review in the August 2019 issue of Current Sports Medicine Reports. Among the...

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When SAD Hits in Summer

Some people experience spring-summer onset seasonal affective disorder (SAD), also called summer depression. As the name suggests, summertime SAD begins in spring or summer and lasts until the fall or...

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How Much of Your Happiness Is Under Your Control?

Do you know the happiness pie chart? If you’ve read a book or listened to a talk about happiness in the past 15 years, there’s a good chance you heard that 50 percent of our happiness is determined by...

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Coping with COVID-19 Isolation

The COVID-19 pandemic, and the sweeping measures of communities around the world to limit its deadly toll, have profoundly altered the way we live and interact. In large swaths of the United States,...

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Resources for Help

Recovering from the fear and social isolation of the COVID-19 pandemic likely won’t be easy for many of us. If you’re struggling with feelings of loneliness, anxiety, confusion, or depression, here are...

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